This feels somewhat like cheating, as I experimented with Prezi last summer, but I'm going to post about it anyway!
I decided to try using Prezi last summer when I was creating a presentation for our KU training. We were to make a PowerPoint and use it to train those in our group in a specific Content Enhancement Routine. I was halfway through the PowerPoint and became sidetracked one night watching a Ted Talk, and ended up on the Prezi website. I decided I would try it out, and was quickly won over. I found it to be very easy and intuitive to create a basic Prezi, and I now prefer it to PowerPoint. To me it is more dynamic and easier to manipulate. I like being able to see the whole presentation as if it is laid out on the table and feel it appeals to my natural inclination to pile things rather than file things.
I have since talked with students about it as an alternative to PPT, and one student has experimented as well. I think it is a great tool and a good option for students who are looking for something more dynamic to create presentations with.